Associate Professor, Medical Oncology, Department of Small Animal Clinical Sciences
Program Focus
Spontaneous cancers in pet animals offer a unique translational research opportunity for cancer imaging and drug development. Companion animals are genetically diverse and exposed to many of the same environmental influences as their owners. Canine cancer patients have been successfully used in numerous studies to provide translatable pharmacokinetic and pharmacodynamic data, and these trials have informed on the scheduling/dosing of small molecular inhibitors in humans. My research focuses on animal cancer patients as a model for pharmacological intervention in combination with non-thermal tumor ablation, and their sequelae on locoregional and distant tumor control.
Selected Publications
Investigation of the immunostimulatory response to high intensity focused ultrasound in dogs with naturally-occurring solid tumors 01/01/18-03/01/20
Focused Ultrasound Foundation (PI: Dervisis, Co-Is: Allen, Daniel, Klahn, Ruth)
Development and application of non-thermal high frequency IRE to treat hepatic tumors 04/01/20-03/31/25
5R01CA240476 NCI (PI: Davalos, Co-Is: Iannitti, Mckillop, Dervisis, Robertson)
High-Frequency Irreversible Electroporation (H-FIRE) for the treatment of canine hepatocellular carcinoma 05/01/20-04/30/22
Veterinary Cancer Society, Gordon Theilen Resident Research Award (PI: Dervisis, Co-Is: Carroll, Allen, Davalos)
High-Frequency Irreversible Electroporation (H-FIRE) for the treatment of metastatic liver disease 07/01/21-06/30/22
Veterinary Memorial Fund (PI: Dervisis, Co-Is: Carroll, Allen, Davalos)