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Photo of Kylene Kehn-Hall
Professor, Virology, Department of Biomedical Sciences and Pathobiology

Program Focus

  • Encephalitic alphaviruses, Rift Valley fever virus, and SARS-CoV-2
  • Identifying critical host factors that are necessary for viral replication and/or pathogenesis
  • Evaluating small molecule inhibitors that target essential host-based events for their therapeutic potential
  • Developing novel diagnostic tools to enable the early detection of viral infections

Selected Publications

Lin SC, Lehman C, Stewart AK, Panny L, Bracci N, Wright JLC, Paige M, Strangman WK, Kehn-Hall K. Homoseongomycin, a compound isolated from marine actinomycete bacteria K3-1, is a potent inhibitor of encephalitic alphaviruses. Antiviral Res. 2021 May 6:105087. doi: 10.1016/j.antiviral.2021.105087.PMID: 33965437

Lin SM, Lin SC, Hsu JN, Chang CK, Chien CM, Wang YS, Wu HY, Jeng US, Kehn-Hall K, Hou MH. Structure-Based Stabilization of Non-native Protein-Protein Interactions of Coronavirus Nucleocapsid Proteins in Antiviral Drug Design. J Med Chem. 2020 Mar 26;63(6):3131-3141. doi: 10.1021/acs.jmedchem.9b01913. Epub 2020 Mar 11

Lundberg L, Pinkham C, de la Fuente C, Brahms A, Shafagati N, Wagstaff KM, Jans DA, Tamir S, Kehn-Hall K. Selective Inhibitor of Nuclear Export (SINE) Compounds Alter New World Alphavirus Capsid Localization and Reduce Viral Replication in Mammalian Cells. PLoS Negl Trop Dis. 2016 Nov 30;10(11):e0005122. PMID: 27902702

For an up-to date list of publications see Dr. Kehn-Hall's ResearchGate profile